Baseshift Blog

Genomics lab operations, pricing, and AI annotation

Practical perspectives for lab directors and researchers evaluating variant annotation tools, VCF analysis pipelines, and AI-driven clinical genomics.

Latest Articles

Exome Variant Analysis in Under 60 Minutes — How Baseshift Works

Manual annotation takes 3–6 hours. Baseshift automates ClinVar lookups, gnomAD frequency checks, HGVS notation, and gene panel filtering. Here's the full pipeline — from VCF upload to clinical PDF.

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Why Genomics Labs Are Overpaying for Variant Annotation

Enterprise platforms charge $50–200 per sample for annotation you can do in 90 seconds. We break down what's actually happening under the hood, why pricing hasn't budged with compute costs, and what lab directors are doing about it.

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